There have been an abundance of dangerous situations occurring at what is now known as Grey Sloan Memorial Hospital.

At its best,Grey’s Anatomysuccessfully balanced patients' medical problems with the doctors' personal issues.

With these combined, fans never really know what to expect fromGrey’s Anatomy.

The-10-Best-Medical-Cases-in-‘Grey’s-Anatomy’,-Ranked

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Even the guest characters who were only in an episode or two had medical cases that made an impact.

These are the 10 best medical cases onGrey’s Anatomy, ranked.

Typically, these cases have meant great opportunities for the doctors, and great misfortunes for the patients.

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One of these was a patient with Tree Man Syndrome inthe underratedGrey’sepisode"Superfreak."

This aspect of Meredith’s personal life caused her to empathize with a patient named Shane Herman.

Instead, it turned out that Hubble had swallowed the heads of 10 Judy dolls.

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This case was very memorable, primarily for how strange it was.

Meredith asked Hubble why he swallowed the doll heads, and originally he would not answer.

When he offered to tell her later on, she decided not to know.

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This was a weird case, but Meredith was still able to empathize with Hubble’s feelings of emptiness.

Megan declared that she had superpowers, and it turned out that she could not feel pain.

This was very interesting medical case, especially for how this story was told.

Dr.Miranda Bailey helping a patient with Treeman Syndrome in Grey’s Anatomy

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Alex was able to convince Megan to get the surgery, and then she went back to her parents.

From there, she was a recurring character throughout the season.

She had to get reconstructive surgery on her face due to severe injuries.

Cristina, Izzie, and Meredith treating Shane Harper’s tumor in Grey’s Anatomy

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Alex helped her to choose a face and a name that he had attached to it, Ava.

The combination of amnesia and facial reconstruction caused Ava to struggle with who she was.

Mark had regularly been talked about, due to his affair with Addison.

A sonogram of the swallowed Judy Doll heads in Grey’s Anatomy

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Due to an excess of growths all over his face, Jake had the appearance of a lion.

Jake’s growths had spread on the inside as well, creating a brain tumor.

Andrew had done it because his crush, Lola, was there, and he wanted to impress her.

A young girl sits in a wheelchair and has small cuts on her face in Grey’s Anatomy.

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Multiple of the hospital’s surgeons were involved in this case, making it truly memorable.

Denny did not get the heart, and ended up stuck in the hospital on an LVAD.

While he was in the hospital, Denny and Izzie fell in love.

Ava / Rebecca sitting on a hospital bed looking intently at Alex Karev on Grey’s Anatomy.

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Denny’s medical case was especially intense, due to what Izzie did to get him a heart.

James Carlson was a man who built a bazooka with his best friend.

The bazooka accidentally went off with James right in front of it, burying itself in his chest.

Jesse Plemons as a patient with lionitis in Grey’s Anatomy

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After the bomb was removed, Burke was able to save James' life.

Sadly, the bomb squad member present, Dylan Young, died when the bomb suddenly went off.

This was a very creative and high-stakes medical case, and one ofGrey’s Anatomy’s most intense moments.

Erika Hahn, Cristina Yang, Richard Webber, Miranda Bailey, and Mark Sloan with a patient in Grey’s Anatomy

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After a train crash, two strangers, Bonnie and Tom, were impaled on the same pole.

This medical case was especially memorable due to the complicated moral dilemma.

If the pole was removed, both of them would bleed out.

Jeffrey Dean Morgan in a hospital bed and Katherine Heigl looking at each other in Grey’s Anatomy.

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The doctors essentially let Bonnie die, and it was incredibly emotional.

NEXT:The Best ‘Grey’s Anatomy’ Quotes, Ranked

A doctor and a man in a bomb protection suit work over a patient in surgery on Grey’s Anatomy.

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Monica Keena and Bruce A. Young in neck braces and hospital gowns in Grey’s Anatomy.

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